AWS Architecture Blog
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Agentic antimicrobial resistance surveillance with AWS HealthOmics and Amazon Bedrock AgentCore
This post presents a reference architecture that turns public sequencing data into plain-language answers about antimicrobial resistance (AMR) genes. It pairs AWS HealthOmics for managed genomics processing with a grounded Amazon Bedrock AgentCore agent, so researchers can ask questions without writing bioinformatics code or SQL.
Announcing the AWS Digital Sovereignty Lens for the Well-Architected Framework
October 2026: This post was reviewed and updated for accuracy. Today we’re launching the AWS Digital Sovereignty Lens, a new Well-Architected lens providing customers with extended guidance for designing, building, and operating sovereign workloads on AWS. Customers tell us that digital sovereignty brings a unique set of challenges that existing architecture guidance doesn’t fully address.
Deploy Oracle Database step by step on Amazon EVS with FSx for ONTAP
This post provides step-by-step procedures to deploy Oracle Database on Amazon Elastic VMware Service (Amazon EVS) with Amazon FSx for NetApp ONTAP as NFS datastore storage. You provision storage volumes, mount NFS datastores, install Oracle, and configure SnapMirror replication for cross-region disaster recovery.
Architect highly available Oracle Database on Amazon EVS and FSx for ONTAP
Learn how to architect a highly available Oracle Database environment on Amazon Elastic VMware Service (Amazon EVS) with Amazon FSx for NetApp ONTAP. This post covers EC2 bare metal instance selection, vSAN and FSx storage tiering, NSX networking, and SnapMirror cross-region disaster recovery for enterprises preserving their VMware operational tooling.
Deploy open source Regional availability tools in your VPC
Deploy AWS Regional availability data as infrastructure you own. Capability Insights for AWS runs a self-hosted dashboard in your VPC that auto-refreshes daily, and Workload Analysis narrows the catalog to the services your account actually runs, so your Regional expansion gap analysis focuses only on what you deploy.
Accelerating airline retailing innovation: how Datalex modernized with AWS Experience-Based Acceleration and agentic AI
Datalex, a leader in airline ecommerce, partnered with AWS on a three-day Experience-Based Acceleration (EBA) workshop to prove modernization feasibility. Learn how they migrated a core reservation component from EJB/Java 8 to Spring Boot/Java 21, built a secure CI/CD pipeline, added observability, and integrated agentic AI.
Running multi-day AZ evacuation drills with ARC Zonal Shift
Prove your multi-AZ architecture can sustain a real impairment. This post shows how to run a multi-day (48-72 hour) Availability Zone evacuation drill with ARC Zonal Shift across Amazon ECS, Amazon EKS, Amazon RDS for PostgreSQL, and Amazon Aurora PostgreSQL, with step-by-step CLI commands, prerequisites, observability metrics, and restore procedures.
How MHK built a HIPAA-eligible agentic AI solution on Amazon Bedrock
MHK built the SmartProminence AI Orchestrator, a HIPAA-eligible agentic workflow framework on AWS using Amazon Bedrock, Amazon ECS, and event-driven patterns. It reduced manual medical review effort by 90% and cut new AI feature deployment from months to weeks. Learn how MHK architected this reusable, multi-tenant orchestrator for healthcare AI.
Build adaptive AI interfaces with the AG-UI protocol, agent swarms, and Nova Act on AWS
Learn how to build AI interfaces that automatically adapt to your agents' variable outputs, using the AG-UI protocol for dynamic UI generation, the Strands Agents SDK swarm pattern for explainable multi-agent collaboration, and Amazon Nova Act to integrate legacy systems that lack APIs.
ReadyOn’s Four Walls of tenant isolation on Amazon EKS
ReadyOn runs a multi-tenant platform on Amazon EKS that handles highly sensitive enterprise data. This post describes their Four Walls model: four independent layers of tenant isolation combining Kubernetes namespaces, Karpenter node pools, Amazon VPC security groups, and per-tenant Amazon Aurora databases for zero-trust defense in depth.
How CSIRO built scalable, cost-optimized genomic variant querying on AWS
Learn how researchers at CSIRO, Australia's national science agency, built Serverless Beacon (sBeacon), a scalable serverless solution for securely querying genomic variant data on AWS. sBeacon implements the GA4GH Beacon standard using Amazon S3, AWS Lambda, Amazon DynamoDB, and Amazon Athena to support production-scale clinical and research applications.
How Equinix cut operational overhead with a shared services architecture on Amazon EKS
Equinix, the world's digital infrastructure company, built a shared services architecture on Amazon EKS to eliminate the operational sprawl of its self-managed Kubernetes environment. Learn how a multi-account North Star architecture centralized governance and shared services, delivering 4x faster deployments and 40% less operational overhead.
Building cloud-native PACS on AWS
A hybrid cloud architecture pattern for modernizing medical imaging on AWS. Learn how multi-hospital networks can centralize PACS archives, enable cross-facility interoperability, and use Amazon S3 storage tiers to manage cost and retention at scale.
How DHI Group accelerates generative AI workloads from idea to production using hackathons
Learn how DHI Group partnered with AWS to move generative AI workloads from idea to production using a structured hackathon. This post covers the Hackathon Acceleration Package, the winning ClearanceJobs and AgileATS agentic architecture on Amazon Bedrock AgentCore, and the principles that make hackathons a repeatable path to production.